According to his mother, this soon to be 11 year old is into skulls. I'll admit, I haven't used much skull fabric in my quilts, although I won't say never. I have a turquoise print bearing small skulls in my stash. Yes, you have to look closely to tell they are skulls, but they are skulls nonetheless. I have added this fabric to a couple of my scrappy quilts.
That said, it was with glee that I used the large print skull fabric to make these:

I used the tutorial posted on Vanilla Joy. It's a great tutorial. I did have to make modifications to her instructions due to the directionality of my fabric. That wasn't difficult. However, it did require more fabric.
My supposition was correct: Custom pillowcases are fun to make.